Found 97 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S PHASE1 The purpose of this study is to see if two new malaria vaccines called FMP1...
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WRAIR Clinical Trials Center
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54 PHASE1 Objectives:
Primary:
• To characterize the infectivity of the new lot of ...
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Walter Reed Army Institute of Research
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Trial for Malaria Vaccine Candidate, PfPEBS (P. Falciparum Pre-Erythrocytic and Blood Stage) PHASE1 This study intends to test the hypothesis that the malaria antigen PfPEBS, ...
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Centre Hospitalier Universitaire Vaudois (CHUV)
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Clinical Study of Meplazumab to Treat With Malaria PHASE1 This Phase 1 study will be conducted to explore the dose regimen in humans ...
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Multiple Locations
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Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults PHASE1 This is a randomized, double-blind, placebo-controlled trial to evaluate sa...
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Bagamoyo Research and Training Center of the Ifakara Health Institute
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VAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection NA This is a clinical study to assess the safety of primary, secondary and ter...
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CCVTM, University of Oxford, Churchill Hospital
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A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S PHASE1 The purpose of this study is to assess two types of new malaria vaccines in...
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NIHR WTCRF, University Hospital Southampton NHS Foundation Trust
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